Ankylosing Spondylitis Causing Obstructive Lung Disease and Tricuspid Insufficiency: A Case Report
Published: June 1, 2019 | DOI: https://doi.org/10.7860/JCDR/2019/41550.12894
Amisha, Paras Malik, Monika Pathania, Vyas Kumar Rathaur
1. Student, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
2. Student, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
3. Assistant Professor, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
4. Associate Professor, Department of Paediatrics, Government Doon Medical College, Dehradun, Uttarakhand, India.
Correspondence
Ms. Amisha,
H No. 440-A, Suraksha Colony, Saili Road, Pathankot, Punjab, India.
E-mail: amishagupta2012@gmail.com
Ankylosing Spondylitis (AS) is a chronic progressive inflammatory spondyloarthropathy typically involving the axial skeleton, especially the sacroiliac joints and spine. Genetic predisposition in AS leads to its common association with certain extra-articular diseases-anterior uveitis (25-30%), psoriasis (10%) and inflammatory bowel diseases (50%). Cardiorespiratory involvement in AS is rare and is usually present in long standing disease as restrictive lung disease, conduction abnormalities or aortic insufficiency. Here, we present a case of unusual AS in a 32-year-old non-smoker male with a major involvement of peripheral joints along with spine and chronic obstructive lung disease with apical fibro-bullous cavity and right sided heart failure over a short duration of disease course. His condition was acutely stabilised with diuretics, anti-hypertensive drugs, anti-pyretics, antibiotics and oxygen inhalation followed by maintenance on Non-steroidal anti-inflammatory agents. Hence, in a patient of AS, a strong index of suspicion should be there for both usual and unusual extra-articular manifestations and a complete work-up would help in early diagnosis and treatment.
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